朱遂强，罗利俊，陈辉，唐敏，阮旭中.癫痫患者认知障碍与生存质量的相关研究[J].中华物理医学与康复杂志,2004,(5):
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| 癫痫患者认知障碍与生存质量的相关研究 |
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| DOI： |
| 中文关键词: 癫痫 认知功能 生活质量 |
| 英文关键词: Epilepsy Cognitive function Quality of life |
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| 摘要点击次数: 1581 |
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| 中文摘要: |
| 目的探讨癫痫患者认知功能障碍的发生率及其影响因素，并研究认知障碍对其生存质量（QOL）的影响。 方法采用瑞文标准推理测验（RSPM）分别测评134例正常人及134例癫痫患者的认知功能，比较2组的测验得分情况，并对影响测验得分的多种因素进行相关性分析，最后将癫痫组按有、无认知功能障碍分为2个亚组，研究癫痫患者认知功能障碍对其QOL的影响。 结果本研究中癫痫患者认知功能障碍的发生率为35%，各分测验结果与正常对照组比较，差异均具有显著性意义。癫痫患者的认知功能障碍与起病年龄、病程、发作类型、发作频率及每次发作持续时间等密切相关；癫痫患者QOL与认知功能状况密切相关。 结论本研究中，约35%的癫痫患者有认知功能障碍，起病年龄、病程、发作类型、发作频率及发作持续时间对其影响较大，且认知功能与生存质量密切相关。临床应重视癫痫患者的认知功能状况，尽量减少或避免导致认知功能受损的危险因素发生，以提高癫痫患者的QOL。 |
| 英文摘要: |
| Objective To investigate the cognitive function of epileptic patients and the related factors, and to correlate them with the quality of life（QOL）of these patients. MethodsThe cognitive function of 134 epileptic patients and 134 healthy controls was evaluated by means of Ravens Standard Progressive Matrices (RSPM), and comparisons between them were made. Correlation between the cognitive dysfunction and its related factors was analyzed. Finally, the epileptic group was further divided into two subgroups based on existence or not of cognitive deficit, and the QOL of two subgroups was compared. ResultsThe total incidence of cognitive deficit in epileptic patients was 35%, which was significantly different from the control group. Among the patients who have cognitive deficit, the scores with all the subtest were significantly lower than control group. The factors related to the cognitive function of epileptic patients were the onset age of illness, duration of the disease, frequency of seizures attack before medication, type of seizures, and the duration of seizures. Significant correlation was revealed between the cognitive deficit and the QOL. ConclusionAbout 35% of the epileptic patients had cognitive deficit. The factors contributing to the cognitive function of epileptic patients included the age of onset of illness, duration of the disease, frequency of seizures attack before medication, type of seizures, and the duration of seizures. Cognitive deficit exerted significantly impact on the QOL of the epileptic patients. In order to improve the QOL, we should pay attention to the cognitive function of epileptic patients and eliminate the risk factors related to cognitive dysfunction. |
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