| 次声作用对大鼠记忆功能及隔内侧核和斜角带核胆碱能神经元表达的影响 |
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| 引用本文： | 魏智钧,李玲,陈景藻,贾克勇,饶志仁,邱建勇,刘惠玲.次声作用对大鼠记忆功能及隔内侧核和斜角带核胆碱能神经元表达的影响[J].中华物理医学杂志,2001,23(2):79-82. |
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| 作者姓名： | 魏智钧 李玲 陈景藻 贾克勇 饶志仁 邱建勇 刘惠玲 |
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| 作者单位： | 魏智钧（710032 西安,第四军医大学西京医院理疗康复科）
李玲（710032 西安,第四军医大学西京医院理疗康复科）
陈景藻（710032 西安,第四军医大学西京医院理疗康复科）
贾克勇（710032 西安,第四军医大学西京医院理疗康复科）
饶志仁（第四军医大学神经科学研究所）
邱建勇（第四军医大学神经科学研究所）
刘惠玲（第四军医大学神经科学研究所） |
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| 基金项目： | 全军重点研究课题资助项目（96Z042） |
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| 摘 要： | 目的 探讨次声作用对大鼠记忆功能及斜角带核和隔内侧核胆碱能神经元表达的影响。方法 记忆保持SD大鼠接受16Hz,90dB或130dB次声照射,2h/次
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| 关 键 词： | 次声 记忆 隔内侧核 斜角带核 大鼠 胆碱能神经元 表达 |
| 修稿时间： | 2000年10月17 |
Expression of cholinergic neurons in the memory and medial septal nucleus and nucleus of diagonal band of the rats exposed to infrasound |
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| Abstract: | Objective To explore the influence on memory function and expression of cholinergic neurons in the medial septal nucleus/nucleus of diagonal band(MS/DB) of the rats exposed to 16 Hz infrasound. Methods The SD rats with memory keeping were exposed to infrasound of 16 Hz with intensity of 90dB or 130 dB for 7,14 d and two hours every time in a day,then observed the latency of avoidance response and expression of cholinergic neurons in the MS/DB with immunohistochemical technique at the different time.Results The memory function of rats exposed to 130 dB infrasound were reduced (P< 0.01 ),the number of the cholinergic neurons in the MS/DB was decreased dramatically (P< 0.01 ) ,no difference was observed in the group exposed to 90 dB infrasound. Conclusion Infrasound can induce number of cholinergic neurons in the MS/DB decreased and memory function as well.The effects are related to the intensity and times of infrasound.When the intensity is same,the effect of 14 d group is no signifcant with 7d group. |
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| Keywords: | Infrasound Memory Medial septal nucleus Nucleus of diagonal band Acetyltransferases Rats |
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