文章摘要
米立新,王彦香,张仲,杨联平,张克亮.经皮电神经刺激对周围神经再生的影响[J].中华物理医学与康复杂志,2003,(4):.-
经皮电神经刺激对周围神经再生的影响
  
DOI:
中文关键词: 经皮电神经刺激  周围神经  神经再生
英文关键词: Transcutaneous electrical nerve stimulation  Peripheral nerve  Regeneration
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作者单位
米立新,王彦香,张仲,杨联平,张克亮 050051石家庄河北医科大学第三医院康复中心(米立新、王彦香、张仲、杨联平、张克亮)手外科(张克亮) 
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中文摘要:
      目的探讨经皮电神经刺激(TENS)对周围神经再生的影响。 方法将18只健康白兔按术后取材时间的不同随机分为A、B、C 3组,将各组白兔双侧腓总神经切断后与同侧外膜开窗的胫神经作端侧缝合。白兔左后肢为实验侧,术后给予TENS,每天1次,右后肢不给予电刺激,作为对照侧。3组白兔分别于术后3、6、16周取材,进行大体观察、神经组织学、透射电镜和电生理检查。 结果A、B、C组白兔实验侧腓总神经有髓纤维数,C组实验侧运动神经传导速度、肌肉复合电位波幅均高于相应各组对照侧(P<0.05),各组白兔实验侧腓总神经髓鞘成熟程度优于对照侧。 结论TENS具有促进周围神经再生,提高神经侧支萌出率的作用。
英文摘要:
      Objective To investigate the effect of transcutaneous electrical nerve stimulation(TENS) on peripheral never regeneration in rabbits. MethodsEighteen healthy rabbits were randomized 3 groups (e.g. groups A, B, C). The peroneal nerves on both sides were transected in each animal, with their distal segments sutured to the tibial nerve with epineural windows in an end to side style. TENS was performed in the left hindlimbs of all the rabbits in groups A, B, C for 3, 6, 16 weeks, respectively, the right hindlimb was not treated with TENS and served as control. At the end of the experiment, gross appearance observation, neurohistological and electrophysiological examination were conducted. ResultsCompared with the right hindlimb, the left side had more regenerated myelinated nerve fibers, and the motor nerve conduction velocity, amplitude of compound muscle action potential were larger than that in the right side(P<0.05). ConclusionTENS had beneficial effect on peripheral nerve regeneration, and could promote the peripheral nerve collateral sprouting.
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