文章摘要
黄晓琳,韩肖华,李春芳,胡晓晴,任恕.电针结合磁刺激对脑缺血大鼠脑组织含水量和细胞外钙离子浓度的影响[J].中华物理医学与康复杂志,2003,(4):.-
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电针结合磁刺激对脑缺血大鼠脑组织含水量和细胞外钙离子浓度的影响
  
DOI:
中文关键词: 电针  磁刺激  脑缺血  脑组织含水量  钙离子
英文关键词: Electroacupuncture  Transcranial magnetic stimulation  Cerebral ischemia  Water/calcium content
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作者单位
黄晓琳,韩肖华,李春芳,胡晓晴,任恕 430030武汉华中科技大学同济医学院附属同济医院康复医学科(黄晓琳、韩肖华、李春芳)神经内科(胡晓晴)华中科技大学同济医学院生物医学工程实验室(任恕) 
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中文摘要:
      目的观察电针结合磁刺激对急性脑缺血大鼠脑组织含水量和细胞外钙离子含量的影响。 方法将30只雄性Wistar大鼠随机分成5组:正常组、模型组、电针组、磁刺激组和电针加磁刺激组,每组6只。制作急性大脑中动脉缺血模型,分别施以电针、磁刺激和电针加磁刺激,检测脑组织含水量和局部细胞外钙离子浓度。 结果单纯电针或磁刺激均能降低脑组织含水量和遏止细胞外钙离子浓度降低,而2者合用效果更优。 结论电针结合磁刺激能较好地改善急性脑缺血大鼠脑组织水肿和良性调节细胞外钙离子浓度。
英文摘要:
      Objective To observe the effects of electroacupuncture (EA) combined with transcranial magnetic stimulation(TMS) on water content and extracellular calcium content of brain tissue after cerebral ischemia in rats. MethodsThirty male Wistar rats were employed and divided randomly into 5 groups: the normal group, model group, EA group, TMS group and a EA plus TMS group. After the establishment of models of acute middle cerebral artery occlusion (MCAO), the rats were treated with EA, TMS and EA plus TMS, respectively. Then the water content and extracellular calcium content of the brain tissues were measured. The data were compared and analyzed among the groups. ResultsEA or TMS decreased the water content and inhibit the decrease of extracellular calcium content of brain tissue after cerebral ischemia in rats and better effect could be achieved with the combined use of EA with TMS. ConclusionEA plus TMS can effectively improve the cerebral edema and adjust the extracellular calcium content after cerebral ischemia in rats.
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