| Objective To evaluate the clinical efficacy of comprehensive rehabilitation training for patients with traumatic brain injury(TBI). Methods Totally 321 TBI patients were assigned at random into one of 8 groups. All were given comprehensive rehabilitation training plus operations, regular drug therapy and nursing as required. The patients in groups 1, 2, 3 and 4 were given rehabilitation treatment beginning 3 to 14 days after the TBI. Those in groups 5, 6, 7 and 8 were treated beginning 15 to 30 days after the injury. The patients in groups 1, 2, 5 and 6 were trained once a day, while those in groups 3, 4, 7 and 8 were trained twice daily. The patients in groups 1, 3, 5 and 7 also received hyperbaric oxygen treatment, while those in groups 2, 4, 6 and 8 did not. The cognitive ability, ability in the activities of daily life (ADL) and movement ability of all of the patients were assessed before the experiment and after 1, 2 and 3 months of training using the Mini-mental State Examination (MMSE), the Modified Barthel Index (MBI), the Fugl-Meyer Assessment (FMA) and functional independence measures (FIMs). The experiment thus had a 2×2×2×4 factorial design, and analysis of variance was applied to the observations. ResultsIn all 8 groups, the average scores of FMA, FIM, MBI and MMSE 1, 2 and 3 months after treatment were significantly better than those before treatment (P<0.01). The scores at 3 months of treatment were the highest. Overall, group 3 showed the best therapeutic effect. The average FMA, FIM, MBI and MMSE results were all significantly related to when the intervention began, the frequency of treatment, hyperbaric oxygen treatment and duration of treatment. ConclusionEarly and intense rehabilitation training in combination with hyperbaric oxygen treatment is particularly effective in increasing the cognitive abilities, ADL functionality and movement abilities of TBI patients. |
