肖露，魏凤芹，牟谷萼，陆敏.经颅直流电刺激对脑卒中恢复期Broca失语患者图命名能力的影响[J].中华物理医学与康复杂志,2015,37(11):810-813
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| 经颅直流电刺激对脑卒中恢复期Broca失语患者图命名能力的影响 |
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| DOI： |
| 中文关键词: 失语症 经颅直流电刺激 脑卒中恢复期 Broca失语 Broca区 |
| 英文关键词: Aphasia Transcranial direct current stimulation Stroke Broca′s aphasia Broca′s area |
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| 中文摘要: |
| 目的探讨经颅直流电刺激（tDCS）对脑卒中恢复期Broca失语患者图命名能力的影响。 方法选取5例左侧额叶或基底核区脑卒中恢复期Broca失语患者，采用自身对照方式，对患者分别进行左侧Broca区阳极、阴极、伪刺激tDCS，同时对患者进行图片命名检查，记录正确率，每次间隔时间≥24h。 结果在左侧Broca区实行tDCS阳极刺激、阴极刺激和伪刺激时，患者的图命名平均正确数分别为13.13、9.80和10.15。与阴极刺激和伪刺激下的平均正确数比较，左侧Broca区tDCS阳极刺激可以显著提高脑卒中恢复期Broca失语患者的图命名能力（P<0.05）。 结论左侧Broca区tDCS阳极刺激可显著改善脑卒中恢复期Broca失语症患者的图命名能力，其作用机制可能是tDCS阳极刺激增强了左侧Broca区皮质的兴奋性，提示左侧Broca区及其周围区对于脑卒中恢复期Broca失语症患者的语言恢复非常重要。 |
| 英文摘要: |
| Objective To investigate effects of transcranial direct current stimulation on picture naming by those with Broca′s aphasia recovering from a stroke. MethodsFive patients with Broca′s aphasia 6-12 months post-stroke served as their own controls. They all had lesions of the left frontal gyrus or the basal ganglia. They received either anodic, cathodic or sham stimulation of the left Broca′s area. They were then given a picture naming test. ResultsThe average number of correct namings was 13.13 with anodic stimulation, 9.80 with cathodic and 10.15 with the sham stimulation. Compared with cathodic or sham stimulation, anodic stimulation of the left Broca′s area can improve the picture-naming ability of aphasic stroke patients significantly more effectively. ConclusionsAnodic stimulation of the left Broca′s area can improve the picture-naming of cerebral apoplexy patients with Broca′s aphasia. Such stimulation may increase the excitability of the left cortex, suggesting that the left Broca′s area and its periphery play a very important role in language recovery after stroke. |
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