李曾慧平，刘颂文，励建安，周士枋，戴玲，路鹏.压力治疗及硅酮敷料治疗对增生性瘢痕疗效的短期研究[J].中华物理医学与康复杂志,2004,(8):
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| 压力治疗及硅酮敷料治疗对增生性瘢痕疗效的短期研究 |
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| DOI： |
| 中文关键词: 增生性瘢痕 压力治疗 硅酮敷料治疗 对照研究 |
| 英文关键词: Hypertrophic scar Pressure therapy Silicone gel sheeting Control study |
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| 中文摘要: |
| 目的采用客观的测试来比较硅酮敷料和压力治疗增生性瘢痕2个月后的效果。 方法将96例具有增生性瘢痕的患者随机分为压力治疗组、硅酮敷料（cica care）组、压力及硅酮敷料综合治疗组（综合治疗组）和对照组。除对照组外，所有患者接受为期2个月的治疗。 结果温哥华瘢痕量表总分显示，只有压力治疗组治疗前、后的差异有显著性意义。超声测量仪和色谱仪所测结果的双因素重复方差分析显示差异无显著性意义。配对t检验显示，与对照组相比，压力治疗组、硅酮敷料组以及综合治疗组在2个月后瘢痕厚度的治疗差异均有显著性意义，但3个治疗组之间的差异无显著性意义。在颜色参数方面，压力治疗组瘢痕的亮度(P<0.01)和红色(P<0.05)改变的差异有显著性意义；硅酮敷料组瘢痕黄色(P<0.01)变化的差异有显著性意义。 结论根据初步的结果，压力治疗及综合治疗对减低增生性瘢痕厚度有较好效果。硅酮敷料治疗对改善瘢痕的血管增生和色素较为有效。 |
| 英文摘要: |
| Objective To investigate the effect of pressure therapy and silicone gel on controlling the hypertrophic scar in Chinese population. MethodsNinety-six patients recruited in the Jiangsu Peoples First Affiliated Hospital, aged 21.25 (SD=19.37) were randomly allocated into 4 groups: control group, pressure therapy group, silicone gel sheeting(SGS) group and combined treatment group. Each subject was given a treatment programme lasting for two months Vancouver Scar Scale was used to assess the progress of scar. The spectrocolorimeter and the ultrasound advancement (Tissue Ultrasound Palpation System) were employed to collect the color and whole thickness of scar, respectively. Two-way repeated analysis was used to analyze the interaction effect of time and treatment and paired t-test was used to analyze the effect over time in each treatment. ResultsTotal score of Vancouver Scar Scale indicated significant change in pressure therapy (P=0.038) and silicone gel sheeting (P=0.02) groups only. Paired t-test showed that the scar thickness in pressure therapy group, silicone gel sheeting (cica-care) and combined groups have significant difference after 2 months of application when compare with control group, but no difference among treatment groups. Among the color parameters, only redness and lightness were significantly changed in pressure therapy group, and only yellowness was significantly changed in SGS group. ConclusionPressure therapy and combined therapy were more effective in reducing the thickness of scar, whereas silicone gel sheeting (cica-care) was more effective in improving scar pigmentation. |
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