文章摘要
吴含,朱奕,王石艳,王盛,张勤,杨思雨,程宏,马锦辉,王彤.有氧运动操对轻度认知障碍的影响[J].中华物理医学与康复杂志,2016,38(2):113-117
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有氧运动操对轻度认知障碍的影响
  
DOI:
中文关键词: 有氧运动  轻度认知障碍  认知功能
英文关键词: Aerobic exercise  Cognitive impairment  Cognition
基金项目:江苏省科技支撑计划—社会发展项目(BE2013724)
作者单位
吴含,朱奕,王石艳,王盛,张勤,杨思雨,程宏,马锦辉,王彤 210029南京南京医科大学第一附属医院康复医学中心(吴含、朱奕、王石艳、王盛、张勤王彤)神经内科(杨思雨)南京脑科医院(程宏)加拿大渥太华大学流行病学院(马锦辉) 
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中文摘要:
      目的观察有氧运动操对轻度认知障碍(MCI)患者的影响。 方法将MCI患者60例按随机数字表法分为治疗组和对照组,治疗组29例,对照组31例。治疗组在节奏性强的音乐引导下进行运动操训练,对照组仅接受宣传教育,未进行任何干预。于训练前和治疗3个月(训练后)分别对2组患者进行MMSE评分、MoCA评分、韦氏逻辑记忆评分、韦氏数字广度评分、连线测试、符号数字评测、社会功能状况(FAQ)评分、生命质量(SF-36)评分以及事件相关电位(听觉诱发电位P300)检查。 结果训练后,治疗组MMSE评分、MoCA评分、韦氏逻辑记忆量表评分、连线测验A、连线测验B、符号数字模式测试、SF-36评分及P300潜伏期分别为(28.0±1.3)分、(24.6±2.3)分、(17.5±3.8)分、(66.2±24.5)s、(158.3±48.7)s、(35.6±8.8)个、(113.6±17.7)分、(422.0±40.0)ms,与组内训练前比较,差异均有统计学意义(P<0.05),而对照组仅MoCA评分与组内训练前比较,差异有统计学意义(P<0.05);且训练后,治疗组的韦氏逻辑记忆测试和连线测验B与对照组训练后比较,差异均有统计学意义(P<0.05)。线性回归分析显示,韦氏逻辑记忆分值和运动操训练呈正相关(P<0.01),而连线试验B与运动操训练呈负相关(P<0.01)。 结论有氧运动可显著改善MCI患者认知功能。
英文摘要:
      Objective To evaluate the effects of aerobic training on elderly persons with mild cognitive impairment (MCI). MethodsSixty patients with MCI were randomized into a treatment group and a control group, each of 30. The patients in the treatment group received 3 months of group gymnastics training which involved aerobic exercise to rhythmic music. Those in the control group accepted only health education. All of the subjects took cognitive assessments, were rated using functional activities questionnaire (FAQ) and a quality of life scale, and had their P300 auditory event-related potentials measured at enrollment and after the 3 months. ResultsThere were no significant differences between the 2 groups before the intervention. After the 3 months of training the treatment group had improved significantly in terms of most of the cognitive assessments (MMSE, MoCA), the revised Wechsler Memory Scale, logical memory, the trail-making test and the symbol digit modalities test). SF-36 was also significantly improved in the treatment group after the 3 months of training. ConclusionAerobic training can significantly improve the cognitive functioning of patients with MCI.
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