杨志军,任山常,杨进华,等.不同运动方式对中年高血压患者炎症反应、内皮功能及动态血压的影响[J].中华物理医学与康复杂志,2024,46(11):967-972
扫码阅读全文
|
| 不同运动方式对中年高血压患者炎症反应、内皮功能及动态血压的影响 |
|
| |
| DOI：10.3760/cma.j.cn421666-20240624-00161 |
| 中文关键词: 有氧运动 抗阻训练 高血压 炎症反应 内皮功能 动态血压 |
| 英文关键词: Aerobic exercise Resistance training Hypertension Inflammation Endothelial functioning Blood pressure |
| 基金项目: |
|
| 摘要点击次数: 880 |
| 全文下载次数: 1366 |
| 中文摘要: |
| 目的 对比不同运动方式对中年高血压患者炎症反应、内皮功能及动态血压（ABP）的影响，为优化康复运动处方提供参考资料。 方法 采用随机数字表法将90例中年高血压患者分为有氧运动组、抗阻训练组及对照组，每组30例。3组患者均保持日常生活习惯及用药方式不变，在此基础上有氧运动组、抗阻训练组患者分别辅以有氧运动训练或抗阻运动训练，3组患者干预时间均为12周。于干预前、干预12周后评估各组患者炎症因子含量、内皮功能以及24 h ABP等指标变化情况。 结果 入选患者对有氧运动或抗阻训练均耐受良好。与组内干预前及同期对照组比较，干预后有氧运动组、抗阻训练组日间收缩压（SBP）和24 h SBP均显著降低（P<0.05），血流介导的血管舒张功能（FMD）指数明显增加（P<0.05），此外有氧运动组血浆一氧化氮（NO）和白细胞介素-10（IL-10）含量均明显增加（P<0.05），C-反应蛋白（CRP）、单核细胞趋化蛋白-1（MCP-1）、血管细胞黏附分子-1（VCAM-1）、血凝素样氧化低密度脂蛋白受体-1（LOX-1）及内皮素-1（ET-1）含量均显著降低（P<0.05）；对照组上述各项指标干预前、后均无显著变化（P>0.05）。 结论 规律有氧运动或抗阻训练均有利于控制中年高血压患者血压及降低心血管疾病发生风险，并以有氧运动的干预效果更佳。 |
| 英文摘要: |
| Objective To compare the effects of different exercise modes on inflammation, endothelium functioning and the ambulatory blood pressure (ABP) of middle-aged hypertensive patients, so as to provide a basis for optimizing rehabilitation training prescriptions. Methods Ninety persons with hypertension were randomly divided into an aerobic exercise group, a resistance training group and a control group, each of 30. All maintained their routine daily living habits and medications. In addition, the aerobic exercise group performed aerobic exercise, while the resistance training group took resistance exercise for twelve weeks. Inflammatory response, endothelium functioning and 24-hour ABP were evaluated before and after the experiment. Results The subjects tolerated the different exercises well. After the experiment, the daytime systolic blood pressure (SBP) and 24-hour SBP of those in both exercise groups had decreased significantly, on average. Flow-mediated dilation had increased significantly. The average plasma nitric oxide and interleukin-10 levels had increased significantly, and the average C-reactive protein, monocyte chemoattractant protein-1, vascular cell adhesion molecule-1, lectin-like oxidized LDL receptor-1, and endothelin-1 levels had decreased significantly in the aerobic exercise group, but not in the control group. Conclusions Both regular aerobic exercise and resistance training benefit blood pressure control and reduce the risk of cardiovascular disease, at least among middle-aged persons with hypertension. Aerobic exercise tends to have the better effect. |
|
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|
