穆景颂,倪朝民,吴鸣,等.中老年脑出血患者下肢深静脉血栓形成的血液指标分析[J].中华物理医学与康复杂志,2022,44(9):784-787
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| 中老年脑出血患者下肢深静脉血栓形成的血液指标分析 |
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| DOI：10.3760/cma.j.issn.0254-1424.2022.09.004 |
| 中文关键词: 脑出血 中老年 深静脉血栓形成 下肢 血液指标 |
| 英文关键词: Cerebral hemorrhage Middle-age Deep venous thrombosis Lower extremity Blood indexes |
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| 中文摘要: |
| 目的 探讨中老年脑出血患者并发下肢深静脉血栓（DVT）的血液指标特点。 方法 回顾性分析2015年8月至2017年8月中国科学技术大学附属第一医院（安徽省立医院）康复医学科收治的脑出血患者77例，入院3日内对这77例脑出血患者进行下肢静脉彩色多普勒超声（彩超）检查，根据下肢静脉彩超表现，将其分为DVT组（18例）和非DVT组（59例）。收集2组患者入院第2日清晨的血常规、生化、凝血象、D-二聚体检查结果，并采用t检验和秩和检验对2组患者上述检查结果中的血白细胞、中性粒细胞百分比、血小板、白蛋白、球蛋白、尿素氮、肌酐、尿酸、空腹血糖、电解质、纤维蛋白原和D-二聚体等参数进行统计学分析。 结果 经统计学分析，DVT组的白蛋白、尿酸和钙的水平分别为（33.35±3.99）g/L、（198.98±65.69）umol/L和（2.18±0.15）mmol/L，均显著低于非DVT组，差异均有统计学意义（P＜0.05）；而其空腹血糖和D-二聚体水平则均显著高于非DVT组，差异均有统计学意义（P＜0.05）。 结论 血尿酸、钙和白蛋白水平的降低，以及空腹血糖和D-二聚体水平的增高与脑出血患者DVT的发生有关，即临床治疗过程中应保持正常的血尿酸、钙、白蛋白和空腹血糖水平，积极降低D-二聚体，才可更有效地预防DVT的发生。 |
| 英文摘要: |
| Objective To document the blood indexes of middle-aged and elderly intracerebral hemorrhage (ICH) patients complicated with deep vein thrombosis (DVT). Methods A retrospective analysis was conducted of 77 hospitalized ICH patients using venous color Doppler ultrasonography within 3 days of admission. According to the results, they were divided into a DVT group (18 cases) and a non-DVT group (59 cases). The blood routine, biochemistry, coagulation, and D-dimer examinations were conducted on the 2nd day after admission. T-tests and rank sum tests tested the significance of any differences between the groups in average white blood cell counts, neutrophil percentages, platelets, albumin, globulin, fasting blood glucose, urea nitrogen, creatinine, uric acid, electrolytes, fibrinogen or D-dimer. Results The average levels of albumin, uric acid and calcium in the DVT group were significantly lower than in the non-DVT group. The average levels of fasting blood glucose and D-dimer were significantly higher. Conclusions Decreased serum uric acid, calcium and albumin levels, together with increased fasting blood glucose and D-dimer are related to the occurrence of DVT in ICH patients. To reduce the risk of DVT it is important to maintain normal levels of serum uric acid, calcium and albumin and to limit D-dimer and fasting blood glucose. |
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