范起萌,杜青,周璇,等.青少年特发性脊柱侧凸畸形角度与心肺运动耐力相关性观察[J].中华物理医学与康复杂志,2022,44(5):437-441
扫码阅读全文
|
| 青少年特发性脊柱侧凸畸形角度与心肺运动耐力相关性观察 |
|
| |
| DOI：10.3760/cma.j.issn.0254-1424.2022.05.012 |
| 中文关键词: 青少年特发性脊柱侧凸 Cobb角 心肺运动试验 心肺运动耐力 |
| 英文关键词: Adolescent idiopathic scoliosis Cobb angle Cardiopulmonary exercise testing Cardiopulmonary exercise endurance Scoliosis |
| 基金项目:上海市卫生健康委员会卫生行业临床研究专项（202040292）；上海市卫生健康委先进适宜技术推广项目（2019SY021）；崇明区医学重点专科项目； 国家自然科学基金面上项目（81972030）；促进市级医院临床技能与临床创新能力三年行动计划项目（SHDC2020CR3041B） |
|
| 摘要点击次数: 1859 |
| 全文下载次数: 2317 |
| 中文摘要: |
| 目的 探讨青少年特发性脊柱侧凸（AIS）畸形角度与心肺运动耐力的相关性。 方法 纳入上海交通大学医学院附属新华医院康复医学科就诊且符合入选标准的64例AIS患者临床资料，所有患者均行心肺运动试验（CPET）评估及拍摄站立位脊柱全长X线片，组间比较采用独立性t检验，用Pearson相关、多元线性回归和两分段线性回归分析AIS患者Cobb角与心肺运动耐力的相关性。 结果 Pearson相关分析显示，Cobb角与最大潮气量（VTmax）呈显著负相关（r=-0.345，P＜0.001），与呼吸频率（RR）呈显著正相关（r=0.273，P＜0.05）。调整性别、年龄、身高和体重后，多元线性回归分析结果显示，Cobb角与VTmax呈显著的负相关性（β=-0.013，P＜0.05），与RR呈显著的正相关性（β=0.421，P＜0.05）；Cobb角与心肺运动耐力水平呈非线性关系，当Cobb角＞34°时，Cobb角每增加1°，心肺运动耐力降低的概率增加了1.399倍（P＜0.05）；当Cobb角≤34°时，随着Cobb角每增加1°，患者心肺运动耐力降低的概率增加0.873倍，但差异无统计学意义（P＞0.05）。 结论 AIS患者的Cobb角与运动过程中的通气功能呈负相关，Cobb角34°以上的AIS患者畸形角度越严重，心肺运动耐力越差。 |
| 英文摘要: |
| Objective To quantify any correlation between the severity of spinal curvature of an adolescent with idiopathic scoliosis and their cardiopulmonary exercise endurance. Methods The cardiopulmonary exercise test (CPET) results and the full-length spinal X-rays in a standing position of 64 adolescents with idiopathic scoliosis were reviewed retrospectively. Independent t-tests were used to compare the two datasets obtained from those with left or right thoracic scoliosis. The correlation between the Cobb angle and cardiopulmonary exercise endurance was analyzed using Pearson correlation coefficients, multiple factor linear regression and two-stage linear regression. Results After adjusting for gender, age, height and weight, the multiple linear regression analysis showed that the Cobb angle was significantly negatively correlated with maximum tidal volume (β=-0.013) and significantly positively correlated with the rate of respiration (β=0.421). The relationship between the Cobb angle and cardiopulmonary exercise endurance was non-linear. With a Cobb angle > 34°, a 1° increase reduces cardiopulmonary exercise endurance by a factor of 1.4 on average. At smaller Cobb angles the corresponding increase is about 0.87 times. Conclusions The Cobb angle is a negative predictor of ventilation during exercise among adolescents with idiopathic scoliosis. The more severe a patient′s spinal curvature, the lower the cardiopulmonary exercise endurance is likely to be. |
|
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |
