张园园,冯慧,开绍江,等.有氧结合抗阻训练对原发性高血压患者血压变异性及血液相关指标的影响[J].中华物理医学与康复杂志,2019,41(5):348-352
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| 有氧结合抗阻训练对原发性高血压患者血压变异性及血液相关指标的影响 |
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| DOI：DOI:10.3760/cma.j.issn.0254-1424.2019.05.008 |
| 中文关键词: 有氧运动 抗阻训练 高血压 血压变异性 动脉硬化 脂蛋白磷脂酶A2 |
| 英文关键词: Aerobic exercise Resistance training Hypertension Blood pressure variability Arteriosclerosis Lipoprotein phospholipase A2 |
| 基金项目:南京市医学科技发展基金项目（YKK15201） |
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| 中文摘要: |
| 目的 观察有氧结合抗阻训练对原发性高血压患者血压变异性（BPV）及血液相关指标的影响。 方法 将90例原发性高血压患者按照随机数字表法分为常规治疗组、有氧运动组、联合治疗组，每组30例。3组患者均给予常规降压药物治疗，有氧运动组在常规基础上增加有氧运动训练，联合治疗组在有氧运动组基础上增加抗阻训练。治疗前、治疗12周后（治疗后），观察3组患者24 h收缩压（SBP）、舒张压（DBP）的平均值及标准差，进行血液指标检查，计算血浆致动脉硬化指数。 结果 治疗前，3组患者24hSBP、24hDBP及24hSSD、24hDSD比较，差异均无统计学意义（P>0.05）。与组内治疗前比较，3组患者治疗后24hSBP、24hDBP均有所下降（P<0.05）。与常规治疗组比较，有氧运动组、联合治疗组治疗后24hSBP、24hDBP均显著下降（P<0.05）。与有氧运动组治疗后比较，联合治疗组治疗后24hSBP［（126.3±7.56）mmHg］、24hDBP［（84.2±5.1）mmHg］均显著下降（P<0.05）。与组内治疗前比较，有氧治疗组、联合治疗组治疗后24hSSD下降（P<0.05）。与常规治疗组治疗后比较，有氧治疗组、联合治疗组24hSSD下降（P<0.05）。3组患者治疗前AIP、Lp-PLA2比较，差异无统计学意义（P>0.05）。与组内治疗前比较，有氧运动组、联合治疗组AIP、Lp-PLA2均有所下降（P<0.05）。与常规治疗组比较，有氧运动组、联合治疗组AIP、Lp-PLA2均有所降低（P<0.05）。与有氧运动组治疗后比较，联合治疗组AIP（2.08±0.23）有所降低（P<0.05）。 结论 降压药物能够降低血压，但不能有效控制血压变异、降低血脂、改善动脉硬化指数。长期有规律的有氧运动能使中老年高血压患者BPV下降，血脂、动脉硬化指数降低、心血管疾病风险降低。有氧运动结合轻中度循环阻力运动在改善上述指标方面的效果较好。 |
| 英文摘要: |
| Objective To observe the effect of aerobic exercise combined with impedance training on the blood pressure variability and other blood-related indexes of patients with hypertension. Methods Ninety patients with essential hypertension were randomly divided into group A, group B and group C, each of 30. All were treated with conventional anti-hypertensive drugs. Groups B and C additionally underwent 40 minutes of aerobic training and group C also received resistance training. There were 3 training sessions a week for 12 weeks. Each subject′s 24 h systolic blood pressure (24hSBP), 24 h diastolic blood pressure (24hDBP) and their standard deviations were observed before and after the 12 weeks. Blood indexes were examined and a plasma arteriosclerosis index was calculated. Results Before the treatment, there were no significant differences in any of the average measurements among the three groups. After the treatment, the average 24hSBP and 24hDBP of all three groups had decreased significantly, but larger decreases were observed in groups B and C. Compared with group B, the average 24hSBP and 24hDBP of group C had decreased significantly more. The average levels of atherogenic index of plasma (AIP) and lipoprotein phospholipase A2 of groups B and C were significantly lower than before the treatment and also significantly lower than group A′s average. The decrease in group C was significantly greater than in group B. Conclusions Anti-hypertensive drugs can lower blood pressure, but cannot effectively control blood pressure variation, reduce blood lipids or improve the arteriosclerosis index. Long-term, regular aerobic exercise can decrease these indicators and reduce cardiovascular disease risk in elderly patients with hypertension. Aerobic exercise combined with mild to moderate circulatory resistance exercise is more effective than aerobic exercise alone. |
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