文章摘要
卢文杰,潘亮,韩战营,王徐乐,王玺,邱春光.运动训练对左室射血分数保留心力衰竭患者活动耐量及生活质量的影响[J].中华物理医学与康复杂志,2018,40(4):267-271
运动训练对左室射血分数保留心力衰竭患者活动耐量及生活质量的影响
Effects of exercise on activity tolerance and life quality after heart failure for patients with a preserved ejection fraction
  
DOI:
中文关键词: 运动训练  射血分数保留心力衰竭  活动耐量  生活质量
英文关键词: Exercise  Heart failure  Activity tolerance  Quality of life
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作者单位
卢文杰,潘亮,韩战营,王徐乐,王玺,邱春光 450052 郑州郑州大学第一附属医院心血管内科 
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中文摘要:
      目的 观察个体化运动训练对左室射血分数保留心力衰竭患者活动耐量及生活质量的影响。 方法 采用随机数字表法将108例左室射血分数(LVEF)保留心力衰竭患者分为运动训练组(55例)和对照组(53例)。对照组给予常规优化药物治疗,运动训练组在对照组用药基础上辅以个体化运动训练。于入选时及12个月后随访时分别采用LVEF、6分钟步行距离测试(6MWD)及明尼苏达心功能不全生命质量量表(MLHFQ)对2组患者活动耐量、生活质量情况进行评定,同时记录观察期间2组患者不良事件发生情况。 结果 12个月后随访时2组患者LVEF组间差异无统计学意义(P>0.05);运动训练组6MWD[(409.9±66.9)m]及MLHFQ评分[(37.8±3.6)分]均显著优于对照组(均P<0.05)。12个月后随访时2组患者LVEF均较入选时无明显改善(均P>0.05);运动训练组6MWD较入选时显著改善(P<0.05),而对照组无明显改善(P>0.05);运动训练组及对照组MLHFQ评分均较入选时显著改善(均P<0.05)。观察期间2组患者不良事件发生情况组间差异无统计学意义(P>0.05)。 结论 个体化运动训练可显著改善左室射血分数保留心力衰竭患者活动耐量及生活质量,同时还具有较好的安全性,但对患者射血分数的影响不显著。
英文摘要:
      Objective To observe the effect of individualized exercise programs on the activity tolerance and life quality of heart failure patients with a preserved ejection fraction. Methods Heart failure patients with a preserved left ventricular ejection fraction (LVEF) were randomized to an exercise training group (n=55) or a control group (n=53). Both groups were given optimized heart failure drug therapy, while the exercise training group was additionally provided with individualized exercise training. The LVEFs, 6-minute walking distances (6MWDs), Minnesota living with heart failure questionnaire (MLHFQ) scores and adverse events were noted before the experiment and after 12 months of the intervention. Results After one year, no significant differences were found in the groups′ average LVEFs or in the incidence of adverse events, while the average 6MWD and the average MLHFQ score of the exercise training group were significantly better than those of the control group. The average MLHFQ score decrease (7.8 points) was statistically and practically significant. Conclusion Individualized exercise training can significantly improve the activity tolerance and quality of life of patients with a preserved ejection fraction. It is safe, but the impacts on the ejection fraction are small.
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