文章摘要
郭敬民,欧萍,卢国斌,钱沁芳,杨式薇,黄艳,谢燕钦,刘桂华,黄龙生,施晓茜.早产儿序贯综合预防干预方法及对智能发育疗效的影响[J].中华物理医学与康复杂志,2018,40(2):123-126
早产儿序贯综合预防干预方法及对智能发育疗效的影响
The effect of sequential, comprehensive, preventive intervention on the development of premature infants′ intelligence
  
DOI:
中文关键词: 早产儿  序贯综合预防干预  智能发育  近期疗效  远期疗效
英文关键词: Premature infants  Preventative intervention  Intellectual development  Parent education
基金项目:福建省科技计划社会发展重点项目(2012Y0010);中国疾病预防控制中心妇幼保健中心母婴营养与健康研究项目(2015FYH007);福建省自然科学基金项目(2016J01490)
作者单位
郭敬民,欧萍,卢国斌,钱沁芳,杨式薇,黄艳,谢燕钦,刘桂华,黄龙生,施晓茜 350001 福州福建省妇幼保健院儿童保健中心福建医科大学附属医院 
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中文摘要:
      目的 探讨早产儿序贯综合预防干预方法及对智能发育的疗效观察。 方法 纳入本院符合条件的早产儿病例资料120例,按随机数字表法分为观察组和对照组,每组60例,对照组采取常规干预措施,观察组在此基础上采用序贯综合预防干预的方法,针对性进行早期医疗干预及专业智能强化训练干预,包括新生儿疾病筛查、病房与门诊衔接、早期干预、早教光碟教育以及开展家长健康教育活动等,所有早产儿从出生后开始干预并随访至36月龄,分别于出生12、24和36个月时,采用0~6岁小儿神经心理发育检查表测查婴幼儿的适应能力、精细运动、语言、大运动及社交行为等五大领域的发育水平,测定计算婴幼儿的DQ,并进行统计学分析评判比较。 结果 干预12个月时,2组早产儿的适应性和精细动作比较,差异有统计学意义(P<0.01);干预24个月和36个月时,2组早产儿在语言、适应性、精细动作方面比较,差异均有统计学意义(P<0.05)。观察组早产儿在12、24和36月龄时的DQ值较对照组同时间点均有明显提高(P<0.05)。2组早产儿在12月龄与24月龄时的DQ值组内比较,差异有统计学意义(P<0.05);而在24月龄与36月龄时的DQ值组内比较,差异均无统计学意义(P>0.05)。 结论 早产儿出生后前2年是干预的关键期,此时行序贯综合预防干预可有效促进早产儿的智能发育,改善早产儿近远期生存质量。
英文摘要:
      Objective To explore the effect of sequential and comprehensive preventative measures on the development of premature infants′ intelligence. Methods A cohort of 120 premature infants was randomly divided into an observation group and a control group, each of 60. Both groups were given routine premature infant care, but the observation group was additionally provided with sequential and comprehensive preventive intervention. It included neonatal screening, inpatient-outpatient link-up, and their parents′ watching CDs explaining early childhood education and health education. All of the infants were followed up from birth to 3 years old. Their adaptive capacity, fine motor skills, language acquisition, gross motor skills and social communication were evaluated at 12, 24 and 36 months old using a child intelligence developmental scale for neurological development. Development intelligence quotients (DQs) were calculated and compared. Results After 12 months, significant inter-group differences were observed in adaptability and fine motor control. At 24 and 36 months old there were also significant differences in language skills. At one, two and 3 years old the average DQ of the observation group was significantly higher than that of the control group. Significant within-group differences in average DQ were observed in both groups between 1 and 2 years old, but not between 2 and 3. Conclusion Intervention within two years after birth is critical for premature infants. Timely, sequential, integrated, preventive intervention can promote the development of intelligence and better life quality for premature infants.
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