文章摘要
贺涓涓,郑丰平,郭云蔚,李雷佳,戴萌,窦祖林,温红梅.经皮内镜下胃造口术对吞咽障碍患者吸入性肺炎的影响[J].中华物理医学与康复杂志,2018,40(1):24-27
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经皮内镜下胃造口术对吞咽障碍患者吸入性肺炎的影响
The effect of percutaneous endoscopic gastrostomy on aspiration pneumonia of patients with dysphagia
  
DOI:
中文关键词: 胃造口术  吸入性肺炎  吞咽障碍
英文关键词: Gastrostomy  Aspiration pneumonia  Dysphagia
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作者单位
贺涓涓,郑丰平,郭云蔚,李雷佳,戴萌,窦祖林,温红梅 510630 广州中山大学附属第三医院康复医学科(贺涓涓、戴萌、窦祖林、温红梅)消化内科(郑丰平、郭云蔚、李雷佳) 
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中文摘要:
      目的 探讨经皮内镜下胃造口术(PEG)预防吞咽障碍患者吸入性肺炎的疗效。 方法 回顾性分析我科收治的43例行PEG术患者临床资料,通过分析患者临床表现、实验室检查及影像学检查结果,对PEG前、后患者吸入性肺炎发生率、痰液微生物检查结果和抗生素使用情况进行比较。 结果 与PEG术前相比,PEG术后患者吸入性肺炎发生率降低(临床诊断发生率:90.7% vs 53.5%,P<0.05;影像诊断发生率:70.4% vs 18.5%,P<0.05),β内酰胺酶抑制剂复方制剂的使用较术前下降(37.2% vs 62.8%,P<0.05);PEG术后痰标本铜绿假单孢菌的检出率较术前增加(72.7% vs 31.8%,P<0.05)。 结论 PEG术可减少吞咽障碍患者吸入性肺炎的发生及广谱抗生素的使用,可能增加下呼吸道铜绿假单孢菌的定植。
英文摘要:
      Objective To explore the preventive effect of percutaneous endoscopic gastrostomy (PEG) on aspiration pneumonia in patients with dysphagia. Methods The clinical data of 43 patients undertaking PEG was retrospectively collected and the incidence of aspiration pneumonia, microbiological examination of sputum and antibiotics use before and after PEG in all the patients were compared. Results After PEG, the incidence of aspiration pneumonia decreased significantly from 90.7% to 53.5% according to clinical diagnosis, from 70.4% to 18.5% according to the chest imaging. The use of β-lactamase inhibitor compound decreased significantly, but the detection rate of pseudomonas aeruginosa increased significantly compared with that before PEG. Conclusion PEG can decrease the incidence of aspiration and antibiotics use, and may increase the chances of pseudomonas aeruginosa colonization in the lower respiratory tract.
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