文章摘要
陈运平,梅元武,俞善纯,包敏,张茂悦.脑外伤后综合征患者的脑诱发电位研究[J].中华物理医学与康复杂志,2003,(5):.-
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脑外伤后综合征患者的脑诱发电位研究
  
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中文关键词: 脑外伤后综合征  体感诱发电位  脑干听觉诱发电位  事件相关电位
英文关键词: Post-traumatic brain injury syndrome  Somatosensory evoked potential  Brainstem auditory evoked potentials  Event-related potential
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陈运平,梅元武,俞善纯,包敏,张茂悦 430022武汉华中科技大学同济医学院附属协和医院神经内科 
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中文摘要:
      目的探讨脑外伤后综合征(PTBIS)患者的脑诱发电位改变特点及脑诱发电位对PTBIS患者脑功能的评定价值。 方法对38例PTBIS患者进行正中神经体感诱发电位(SEP)、脑干听觉诱发电位(BAEP)及事件相关电位(ERP)检测,并与性别、年龄相匹配的健康者对比。 结果SEP、BAEP及ERP异常率分别为71.1%、38.9%、50%。SEP异常主要为P15、N60波波峰潜伏期延长和N20波波幅降低,BAEP异常主要为Ⅲ、Ⅴ波波峰潜伏期延长或Ⅰ~Ⅲ、Ⅰ~Ⅴ峰间期延长,ERP异常主要为P3潜伏期延长。 结论多项诱发电位异常提示PTBIS患者存在大脑半球、脑干功能的损害及认知功能障碍,脑诱发电位检查为PTBIS患者的脑功能评定提供了一种敏感、客观的电生理学手段。
英文摘要:
      Objective To investigate the features of evoked potentials in patients with post-traumatic brain injury syndrome(PTBIS) and the value of evoked potentials in evaluating cerebral function for patients with PTBIS. MethodsThirty-eight patients with PTBIS were studied simultaneously with median nerve somatosensory evoked potential (SEP), brainstem auditory evoked potential(BAEP)and event-related potential(ERP).The data of the EPs obtained by any modality in the patients were analyzed in comparison with that of healthy persons matched in sex and age. ResultsThe abnormal ratios of SEP,BAEP and ERP for patients with PTBIS were 71.1%,38.9% and 50%, respectively.The major abnormalities of SEP were the delay of P15,N60 peak latency and decrease of N20 amplitude. The major abnormalities of BAEP were delay of Ⅲ,Ⅴ peak latency orⅠ~Ⅲ,Ⅰ~Ⅴ interpeak latency. The major abnormality of ERP was the delay of P3 peak latency. ConclusionAbnormalities of multimodal evoked potentials indicated that patients with PTBIS had the functional impairment of specific cerebral areas or brainstem and cognitive disturbances. Evoked potential test provides a sensitive and objective electrophysiological means in evaluating cerebral function for patients with post-traumatic brain injury syndrome.
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