汪玉萍，王兴林，梁晓镛，胡洁.强直性脊柱炎患者疲劳症状的量化评定及相关因素分析[J].中华物理医学与康复杂志,2003,(3):.-
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| 强直性脊柱炎患者疲劳症状的量化评定及相关因素分析 |
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| DOI： |
| 中文关键词: 疲劳 强直性脊柱炎 评定 |
| 英文关键词: Fatigue Ankylosing spondylitis Assessment |
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| 摘要点击次数: 3744 |
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| 中文摘要: |
| 目的探讨Bath强直性脊柱炎疾病活动指数量表中疲劳评定项目是否可作为强直性脊柱炎患者疲劳症状的量化评定指标，并探讨疲劳症状的相关因素。 方法应用Bath强直性脊柱炎疾病活动指数量表、Bath强直性脊柱炎功能指数量表、简化McGill疼痛调查量表、睡眠障碍10 cm目测类比法等对93例强直性脊柱炎患者进行评定，并同时进行重测信度检验；以Bath强直性脊柱炎疾病活动指数量表中疲劳项目的评分5分为界，将患者分为疲劳症状明显组和疲劳症状不明显组，并进行疲劳特点及相关因素分析。 结果Bath强直性脊柱炎疾病活动指数量表、Bath强直性脊柱炎功能指数量表和睡眠障碍10 cm目测类比法的重测信度较好。52.69%的患者（n=49）为疲劳症状明显者，其与疲劳症状不明显者相比，年龄、性别比例、起病年龄、病程等无显著差异（P＞0.05），而Bath强直性脊柱炎疾病活动指数量表中腰背痛分、晨僵分、总分、Bath强直性脊柱炎功能指数量表总分、简化McGill疼痛调查量表感觉分、总分及睡眠障碍分显著为高（P＜0.05）。双变量关系分析表明疲劳与疼痛、晨僵、疾病活动性、功能状况和睡眠障碍高度相关。 结论疲劳为大部分强直性脊柱炎患者的主要症状；应用Bath强直性脊柱炎疾病活动指数量表的疲劳项目评分可较好地进行疲劳症状的量化评定；疲劳症状与疼痛、晨僵、疾病活动性、功能状况和睡眠障碍高度相关。 |
| 英文摘要: |
| Objective To investigate if the single-item fatigue question of the Bath Ankylosing Spondylitis Disease Activity Index(BASDAI) is appropriate for measuring fatigue in patients with ankylosing spondylitis(AS), and to identify factors that influence fatigue in these patients. MethodsA total of 93 patients with ankylosing spondylitis were recruited. Patients completed questionnaires on disease activity(BASDAI), functional ability［Bath Ankylosing Spondylitis Functional Index(BASFI)］, the short-form McGill Pain Questionnaire and 10 cm visual analogue scale(VAS) for sleep disturbance. Reliability was assessed with intraclass correlation coefficients. The patients were then dichotomized into a F+group (eg, fatigue is the major symptom) if the BASDAI fatigue scale was ≥5.0 and a F－group(eg, fatigue is the minor symptom) if the fatigue score was ＜5.0. Relationships between fatigue and clinical variables were examined using Pearson's correlation coefficient. ResultsThere was good test-retest reliability of BASDAI, BASFI and 10 cm VAS for sleep disturbance over 24 hours. Fifty-three percent of patients (n=49) were assigned to the F+group, they scored significantly worse when compared with those in the F－group with respect to the results with BASDAI, BASFI, the short-form McGill Pain Questionnaire and 10 cm VAS for sleep disturbance(P＜0.05). After controlling for other factors such as age, sex ratio, age at disease onset and disease duration, it was found that fatigue was highly correlated with pain, stiffness, disease activity, functional disability and sleep disturbance. ConclusionFatigue is a major symptom in majority of the patients with AS, in particular those with more severe disease. Fatigue can effectively be measured with a single-item fatigue question of BASDAI, and appears to be strongly associated with the level of pain, stiffness, disease activity, functional ability and sleep disturbance. |
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