李凤敏，马健，王伟，王铮强，茹玲，周淑梅.蓝紫光照射对烧伤大鼠免疫功能的影响[J].中华物理医学与康复杂志,2003,(11):.-
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| 蓝紫光照射对烧伤大鼠免疫功能的影响 |
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| DOI： |
| 中文关键词: 蓝紫光 大鼠 烧伤 免疫 |
| 英文关键词: Blue=purple light(BPL) Rat Burn Immune function |
| 基金项目:天津医科大学总医院青年基金资助项目（No.9835） |
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| 中文摘要: |
| 目的研究蓝紫光照射对烧伤大鼠免疫功能的影响。 方法将48只大鼠随机分为正常对照组、烧伤对照组及烧伤蓝紫光照射治疗组（治疗组），在烧伤对照组及烧伤蓝紫光组背部皮肤造成大鼠体表面积（BSA）20%深Ⅱ度烧伤模型，并用蓝紫光对治疗组进行照射。测定烧伤后3 d、12 d腹腔吞噬细胞吞噬活性、血清免疫球蛋白含量及肿瘤坏死因子细胞毒性的变化。 结果蓝紫光照射可以显著提高烧伤大鼠腹腔吞噬细胞的吞噬能力，并可提高烧伤大鼠血清IgA含量及调节血清中的TNF水平。 结论蓝紫光照射可通过提高大鼠腹腔吞噬细胞的吞噬能力、调节B=细胞功能、TNF水平来提高机体免疫力，从而促进烧伤创面的愈合。 |
| 英文摘要: |
| Objective To elucidate the effects of blue=purple light (BPL) irradiation on the immune function of burned rats. Methods48 adult Wistar rats were randomly divided into the BPL treatment group, burn control group， and normal control group after replicating 20% BSA deep partial thickness burn models of rats. Changes in phagocytic index, phagocytic rate, level of serum immunoglobin A,G,M and TNF from 3rd day and 12th day after the burn were measured. ResultsAfter irradiation of BPL, the phagocytic index, phagocytic rate and level of serum immunoglobin A,G,M in burned rats were increased when compared with those of the control group. The level of serum TNF post=irradiation was higher than that of the normal control and lower than that of the burn control. ConclusionThe study suggested that BPL irradiation could improve immune function in burned rats. |
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