张宇，张小云.旋转磁场对去卵巢大鼠骨钙含量及其相关因子的影响[J].中华物理医学与康复杂志,2004,(9):
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| 旋转磁场对去卵巢大鼠骨钙含量及其相关因子的影响 |
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| DOI： |
| 中文关键词: 旋转磁场 去卵巢大鼠 骨钙含量 骨碱性磷酸酶 尿脱氧吡啶交联 |
| 英文关键词: Rotary magnetic field Rats Ovariotomy Bone mineral content Bone-specific alkaline phosphatase Deoxypyridinoline crosslinks |
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| 中文摘要: |
| 目的研究旋转磁场对去卵巢大鼠骨钙含量，以及骨碱性磷酸酶（BAP）、尿脱氧吡啶交联（DPD）的影响，并观察旋转磁场对雄性大鼠是否有同样的结果。探索治疗骨质疏松的中药是否与磁场有协同作用。 方法磁场处理实验组大鼠每天处理2 h共15次后,检测各组大鼠骨钙含量、BAP、DPD，并与对照组进行比较。 结果无论雄鼠还是去卵巢的雌鼠，凡经磁场处理后，磁场组的骨钙含量和血清BAP含量明显增加，同时DPD下降，服用中药组的实验结果对上述检测项目没有显著影响。 结论旋转磁场能较短时间内有效的促进BAP的升高和DPD的下降，导致去卵巢大鼠股骨的骨钙含量增加，不但再次验证了磁场能够在短时间内有效的提高去卵巢大鼠的骨密度，而且还证明旋转磁场对雄性大鼠也有同样的作用。 |
| 英文摘要: |
| Objective To observe the effects of rotary magnetic to bone mineral content（BMC）, bone-specific alkaline phosphatase （BAP） and deoxypyridinoline crosslinks （DPD）, and to explore if there is synergistic action between the rotary magnetic field and the Chinese Medicine. MethodsExperimental rats were exposed to the magnetic field 2 hours a day for 15 days then measured BMC, BAP and DPD then compared with that of the control rats. ResultsAfter rotary magnetic treatment, both female and male rats demonstrated a significant increase in BMC and BAP, and a simultaneous decrease in DPD content. Addition of Chinese medicine did not cause any significant difference of these parameters. ConclusionIn rats with ovariotomy, rotary magnetic field can increase BAP and decrease DPD in a short time,and increase bone mineral content. These effects were similar in both female and male rats. |
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